What Are the Stages of Osteoporosis?

2022-11-07 16:24:08 By : Mr. Lane Cao

 Rachael is a freelance healthcare writer and critical care nurse based near Cleveland, Ohio.

David Ozeri, MD, is a board-certified rheumatologist from Tel Aviv, Israel specializing in arthritis, autoimmune diseases, and biologic therapies.

Osteoporosis is a condition that develops over time as your bones get weaker with age. You may not have symptoms early on, but as the disease progresses, your bones will get frailer. This means that breaks and fractures can happen more easily.

This article will explain the stages of osteoporosis, as well as the causes, symptoms, and possible treatments for the condition.

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Osteoporosis is the most common bone disease. A diagnosis of osteoporosis means that your bones have become weakened and frail. This happens with age, but a number of other factors can make the condition worse or speed the disease's progression.

Your bone mass is a measurement of how strong your bones are. According to the Centers for Disease Control and Prevention (CDC), low bone mass can be found in almost half of all Americans over the age of 50. Osteoporosis, the advanced stages of low bone mass, develops in nearly 13% of Americans after age 50.

Osteoporosis affects women more often than men: Almost 20% of people over age 50 with osteoporosis are women, while men account for less than 5%.

Osteoporosis is a condition in which your bones have grown weaker and can break more easily. It's most common with age, and it affects women more often than men.

Bone loss is a natural process. Bone tissue is constantly lost and replaced, but bones become weakened when bone tissue is not replaced as fast as it's lost. Bone mass peaks in the teenage years, and declines throughout adulthood.

The process of bone loss is called resorption. There are a number of things that can increase your rate of resorption without increasing your rate of replacement. Factors that can affect your bone mass and rates of resorption include:

As bone mass is reduced, the entire structure of your bones becomes weaker. In addition to your overall health, there are also conditions or lifestyle choices that can cause bone loss and lead to osteoporosis.

There are several types and stages of bone loss. Osteoporosis is usually classified based on how much bone mass you have lost and what caused the bone loss to happen.

Bone density is measured using a test called dual-energy X-ray absorptiometry (DEXA or DXA). It measures bone mass and density using a measurement called a T-score. The lower the T-score, the lower your bone mass is.

Osteopenia, or a diagnosis of low bone mass, is like "pre-osteoporosis." With this type of bone loss, your bones are weakening, but you are not classified as having osteoporosis. With osteopenia, you have a T score between -1 and -2.5.

Primary osteoporosis describes bone loss that occurs as part of the natural aging process. It is broken up into two subgroups:

Secondary osteoporosis refers to bone loss that happens outside of the normal aging process, most often from nutritional deficiencies or other underlying health conditions. The table below highlights some lifestyle factors and diseases that can contribute to or cause bone loss.

Gastrointestinal conditions (such as IBD or IBS)

Roughly a third of postmenopausal women who have primary osteoporosis also have a secondary cause. Between 50% and 80% of men with osteoporosis have secondary contributing factors.

There are several types of osteoporosis. Your doctor can determine if there is another condition that's causing your bone loss or if it is just part of the normal aging process.

Osteoporosis develops gradually, often with no symptoms at all. Most people do not even know that they have the condition until they experience a break or fracture.

When you're young, your bones grow faster than they break down. At some point in your 20s and 30s, bone resorption and new bone formation reach an equilibrium—meaning that you lose and form bone at the same rate. This can be considered the first stage of osteoporosis because the formation of bone is no longer outpacing bone loss.

You will have no symptoms at this stage. Your bone density scores (T-score) will be normal and range from +1 to -1.

At this stage, you still have no symptoms, but your bone loss is now happening faster than your bone growth. If you experience an injury or have bone mass testing done for another reason, you might be diagnosed with osteopenia. T-scores during this stage range from -1 to -2.5.

When you have reached this stage, you officially have osteoporosis. Again, you may not notice any symptoms, but you are at a higher risk of breaks and fractures even from simple injuries like hitting your leg against a door. In this stage, your T-score is -2.5 or lower.

This is a more severe form of osteoporosis. Outside of breaks and fractures, this is the only stage where you may actually notice the bone loss. The softening and weakening of your bones can cause deformities (such as a bent-over appearance called kyphosis that results from weak bones in your spine) and pain with everyday activities.

In this stage, your T-score is well below -2.5 and you have had one or more breaks or fractures.

There are several stages of osteoporosis. The first two are more like precursors to the actual disease. In the latter two stages, you may have frequent fractures or breaks, experience pain, or even have deformities from bone loss.

While bone density testing is the most exact way to determine your level of bone loss, your doctor will usually start by taking your personal and family medical history, get a list of your health conditions and any medications you are taking, and do a physical exam.

Bone density measurements are taken with a dual energy X-ray absorptiometry (DEXA) scan. This test is similar to an X-ray, but it gives your doctor an actual reading of the mineral density in each square centimeter of bone.

The measurement is given with a T-score, which requires several measurements and takes many factors into account. Your scores are then compared with those of other people in your sex and age group.

All women who are age 65 and older should be screened for osteoporosis with a bone density test, according to the U.S. Preventive Services Task Force (USPSTF). People with certain risk factors, or some women who have been through menopause but are under age 65, should be tested early or more frequently.

If you have been diagnosed with osteoporosis and are taking medications to treat the condition, your bone density scan should be repeated every one to two years.

A bone density scan is the best way to measure bone loss, but if you have had a fragility fracture, it is a sign that you have osteoporosis. In this case, you might be diagnosed even if you have not had a scan.

Treating osteoporosis usually involves taking nutritional supplements to boost your bone health, strengthening the muscles that help support your bones, and taking medications that can reduce bone loss or increase bone density.

Vitamin D and calcium supplements are often used to treat or prevent bone loss. Below are the usage recommendations for these supplements:

If you can, it's best to obtain these nutrients directly from your diet. Try to include foods that are rich in calcium and vitamin D and use supplements only to make up for shortages. Your doctor may also recommend other dosages of these supplements for you based on your health and risk factors.

Always talk to your doctor about starting any new vitamins or supplements. Many supplements can interact with other medications and cause adverse effects.

You cannot directly exercise your bones, but you can strengthen the muscles that are around them. While staying active overall is most important, there are particular activities that can help preserve your bone density.

Types of exercise that support your bones include:

These exercises should be done for at least 30 minutes three times a week. However, you should avoid exercises that could increase your risk of injury or falls.

Medications are sometimes used to help slow or stop bone loss, or to help improve overall bone health. You may not need to take these medications forever. In some cases, you may need to take the medication for only a few years, depending on your risk.

Examples of medications that may be used to treat osteoporosis and bone loss include:

Osteoporosis is usually treated with a combination of lifestyle changes, including diet and exercise, and medications that can slow or stop bone loss and promote new bone growth.

You cannot prevent all forms of osteoporosis—especially those that are caused by underlying diseases or the aging process. However, you can try to slow the process.

Your age, your sex, and your genetics are not factors that you can control, but there are several risk factors that contribute to osteoporosis that you can have an effect on by making lifestyle changes.

You can help prevent bone loss and osteoporosis by:

You cannot stop normal bone loss from aging, but you can slow it and modify certain lifestyle risk factors that contribute to it.

Osteoporosis is a condition in which your bones get weaker over time until you start to have breaks and fractures. You cannot always prevent osteoporosis, but you can slow its progress. If you are in the early stages of bone loss, your doctor can help you identify ways to promote bone growth and slow or stop bone loss.

Everyone loses bone density over time, but for some, these losses can lead to pain and fractures. Women are at a higher risk of developing the condition than men. There are certain activities—like smoking—that can increase your risk.

Talk to your doctor about preventing and screening for osteoporosis. Identifying and modifying risk factors in the early stages of the disease can help slow or stop its progression.

Bone loss is always happening, but in your youth, bone is replaced just as fast or faster than you lose it. Over time, these processes become equal, and eventually, bone loss outpaces replacement. In the early stages of osteoporosis, bone loss is minimal.

You cannot reverse osteoporosis, but you can treat it. Some medications and supplements can help slow bone loss and increase bone density.

Usually you won't know you have bone loss until you have a break or a fracture. Your doctor can perform a bone scan if you have a risk factor for increased bone loss.

Sözen T, Özışık L, Başaran NÇ. An overview and management of osteoporosis. Eur J Rheumatol. December 30, 2016; (1):46-56. doi:10.5152/eurjrheum.2016.048.

Centers for Disease Control and Prevention (CDC). Osteoporosis or low bone mass in older adults: United States, 2017–2018.

Mirza F, Canalis E. Management of endocrine disease: Secondary osteoporosis: pathophysiology and management. Eur J Endocrinol. May 13, 2015;173(3):R131-R151. doi:10.1530/EJE-15-0118.

National Institutes of Health. Bone mass measurement: What the numbers mean.

National Osteoporosis Foundation. Types of bone density tests.

By Rachael Zimlich, BSN, RN  Rachael is a freelance healthcare writer and critical care nurse based near Cleveland, Ohio.

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